Job area Research & Development Activity Corporate Location Marcq-en-Barœul, France Contract type Internship - Stage
Job description
Objective:
Spore formers are an important class of microorganisms that have a wide range of applications in the food and biotech industries.
The intern will contribute to a deeper understanding of spore-forming bacteria and their antibiotic resistance mechanisms, by developing methods for the characterization of spore-forming bacteria compatible with high throughput screening and assessing identifying genes responsible for antibiotic resistance using genomic data and molecular biology tools.
Approach:
The intern will be in charge of:
In-depth literature review on spore former functionalities to identify ideal targets for high-throughput characterization testing. Development of new characterization methods compatible with HTS Genome analysis of spore-forming bacteria to identify genes responsible of antibiotic resistance Construction of GMO-strains to confirm the function of the identified genes. Deliverables:
Detailed report on the optimization of the effectiveness of sporulation and germination of spore-forming bacteria using MTP and high-throughput methods. Identification of antibiotic resistance genes correlated with phenotypic resistance profiles. Qualifications
Education and Experience:
Master or Engineer’s degree in Microbiology/Biology or Food Science. Technical skills:
knowledge in applied microbiology, bacteria physiology, cultivation, and assay development.
Knowledge of bacterial spore formers handling is a plus. Familiarity with bioinformatics tools. Knowledge in genetic engineering.
Previous experience in this domain would be a plus. Fluent in English.
Basic French knowledge is a plus. Writing Skills: English writing abilities. Behavioral skills:
Sense of relationships, positive, pro-active and team spirited. Autonomous and with a critical thinking attitude. Good communication skills, synthetic, able to adapt and convey messages.